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局部麻醉和镇静或全身麻醉联合或不联合阴茎阻滞在儿童行肉切开术:一项前瞻性随机研究。

Meatotomy using local anesthesia and sedation or general anesthesia with or without penile block in children: a prospective randomized study.

机构信息

Pediatric Urology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

出版信息

J Urol. 2011 Feb;185(2):654-7. doi: 10.1016/j.juro.2010.09.119. Epub 2010 Dec 18.

DOI:10.1016/j.juro.2010.09.119
PMID:21172701
Abstract

PURPOSE

Meatotomy is a simple, common procedure for the treatment of meatal stenosis. We compared the outcomes of meatotomy performed using local anesthesia and sedation, and general anesthesia with and without penile block.

MATERIALS AND METHODS

A prospective comparative design was used. Participants included 76 boys 1.5 to 10 years old treated for meatal stenosis at a tertiary, university affiliated, pediatric medical center in 2008. Children were randomly allocated to undergo surgery with sedation and local anesthesia, or general anesthesia with or without penile block. All procedures were performed with the same method by the same surgeon. For local anesthesia EMLA 5% cream (lidocaine 2.5% and prilocaine 2.5%) covered with an occlusive dressing was applied 1 hour preoperatively, and midazolam (in patients younger than 5 years) or nitrous oxide (older than 5 years) was used for sedation. General anesthesia was induced with inhaled sevoflurane, and ropivacaine was used for dorsal penile nerve block.

RESULTS

There was no difference among the groups in pain level intraoperatively (no pain in 92% to 93% of patients), 24 hours postoperatively (no pain in 81% to 88%) or after 1 month, or in complication rates (bleeding in 3 patients, laryngospasm in 2). General anesthesia with penile block was associated with a trend of less dysuria. Quality of void was excellent in 87% of patients at 24 hours and in 70% at 1 month, and parental satisfaction was high (88% to 92%).

CONCLUSIONS

Meatotomy performed using local anesthesia and sedation has an equally good outcome to meatotomy performed using general anesthesia with or without penile block.

摘要

目的

尿道扩张术是治疗尿道口狭窄的一种简单常见的方法。我们比较了在局部麻醉和镇静、全身麻醉加或不加阴茎阻滞下进行尿道扩张术的结果。

材料和方法

采用前瞻性比较设计。2008 年,在一家三级大学附属儿科医学中心,对 76 名年龄在 1.5 至 10 岁之间因尿道口狭窄接受治疗的男孩进行了研究。将这些患儿随机分为三组,分别接受镇静和局部麻醉下手术、全身麻醉加或不加阴茎阻滞下手术。所有手术均由同一位外科医生以相同的方法进行。局部麻醉时,术前 1 小时应用 EMLA 5%乳膏(利多卡因 2.5%和丙胺卡因 2.5%),并用密闭敷料覆盖,对年龄小于 5 岁的患儿应用咪达唑仑,对年龄大于 5 岁的患儿应用笑气镇静。全身麻醉时,采用吸入七氟醚诱导,并用罗哌卡因行阴茎背神经阻滞。

结果

三组患儿术中疼痛程度(92%至 93%的患儿无疼痛)、术后 24 小时(81%至 88%的患儿无疼痛)和术后 1 个月时疼痛程度无差异,并发症发生率也无差异(3 例患儿出血,2 例患儿发生喉痉挛)。虽然全身麻醉加阴茎阻滞与尿道刺激症状较轻有关,但差异无统计学意义。术后 24 小时,87%的患儿排尿质量极好,1 个月时为 70%,父母满意度高(88%至 92%)。

结论

在局部麻醉和镇静下进行尿道扩张术与在全身麻醉加或不加阴茎阻滞下进行尿道扩张术的效果同样好。

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