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外用EMLA乳膏用于成人阴茎小手术的疗效与安全性。

The efficacy and safety of topical EMLA cream application for minor surgery of the adult penis.

作者信息

Gyftopoulos Kostis I

机构信息

Urologic Surgeon, Olympion Hospital, and Department of Anatomy, University of Patras Medical School, Patras, Greece.

出版信息

Urol Ann. 2012 Sep;4(3):145-9. doi: 10.4103/0974-7796.102658.

Abstract

BACKGROUND AND OBJECTIVES

A variety of surgical procedures of the penis can be performed under local anesthesia. We evaluated the efficacy and safety of EMLA cream anesthetic in such procedures.

MATERIALS AND METHODS

In total 330 adult patients were subjected to minor penile surgery including: Complete circumcision (73), short frenulum plasty (168), meatotomy (14), fulguration of penile warts (56) and fulguration of urethral (meatal) warts (19). The level of anesthesia obtained by EMLA cream application along with any adverse effects was recorded.

RESULTS

The use of EMLA on mucosal lesions provided excellent level of local anesthesia in almost all patients (245/246, 99.5%). Anesthesia of skin lesions was in part influenced by the site of application. Circumcision patients showed the lowest efficacy of the EMLA cream as the majority (~80%) required some form of further anesthesia until the completion of the procedure. No significant adverse effects were noted. A transient erythema was present in almost all mucosal applications.

CONCLUSIONS

The topical anesthetic EMLA cream is a useful, efficient and safe tool for minor surgical procedures of the penis at the office setting, with the exception of circumcision, where an additional type of anesthesia is likely to be necessary. Side effects can be kept to a minimum when the suggested doses are respected (especially at mucosal application) and the time allowed for action is carefully tailored to the site of application and the type of procedure.

摘要

背景与目的

多种阴茎外科手术可在局部麻醉下进行。我们评估了复方利多卡因乳膏麻醉剂在此类手术中的有效性和安全性。

材料与方法

总共330例成年患者接受了小型阴茎手术,包括:完全包皮环切术(73例)、短系带成形术(168例)、尿道口切开术(14例)、阴茎疣电灼术(56例)和尿道(尿道口)疣电灼术(19例)。记录使用复方利多卡因乳膏获得的麻醉水平以及任何不良反应。

结果

在几乎所有患者(245/246,99.5%)中,复方利多卡因乳膏用于黏膜病变时提供了良好的局部麻醉水平。皮肤病变的麻醉部分受涂抹部位影响。包皮环切术患者中复方利多卡因乳膏的效果最差,因为大多数患者(约80%)在手术完成前需要某种形式的进一步麻醉。未观察到明显的不良反应。几乎所有黏膜涂抹部位均出现短暂红斑。

结论

局部麻醉剂复方利多卡因乳膏是门诊环境下阴茎小型手术有用、高效且安全的工具,但包皮环切术除外,该手术可能需要额外的麻醉方式。当遵循建议剂量(尤其是在黏膜涂抹时)且根据涂抹部位和手术类型仔细调整作用时间时,副作用可降至最低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf9/3519104/97f122a466b7/UA-4-145-g002.jpg

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