Höfling J F, Anibal P C, Obando-Pereda G A, Peixoto I A T, Furletti V F, Foglio M A, Gonçalves R B
Departamento de Diagnóstico Oral, Universidade Estadual de Campinas, Piracicaba, SP, Brazil.
Braz J Biol. 2010 Nov;70(4):1065-8. doi: 10.1590/s1519-69842010000500022.
The increase in the resistance to antimicrobial drugs in use has attracted the attention of the scientific community, and medicinal plants have been extensively studied as alternative agents for the prevention of infections. The Candida genus yeast can become an opportunistic pathogen causing disease in immunosuppressive hosts. The purpose of this study was to evaluate dichloromethane and methanol extracts from Mentha piperita, Rosmarinus officinalis, Arrabidaea chica, Tabebuia avellanedae, Punica granatum and Syzygium cumini against Candida species through the analysis of Minimum Inhibitory Concentration (MIC). Results presented activity of these extracts against Candida species, especially the methanol extract.
抗菌药物使用中耐药性的增加引起了科学界的关注,药用植物作为预防感染的替代药物已得到广泛研究。念珠菌属酵母可成为机会性病原体,在免疫抑制宿主中引发疾病。本研究的目的是通过分析最低抑菌浓度(MIC)来评估薄荷、迷迭香、小花阿拉比卡、阿维拉纳达黄钟木、石榴和乌墨的二氯甲烷和甲醇提取物对念珠菌属的抗菌活性。结果表明这些提取物对念珠菌属具有活性,尤其是甲醇提取物。