开放性三野与微创食管癌切除术治疗食管癌的比较。

Comparison of open three-field and minimally-invasive esophagectomy for esophageal cancer.

作者信息

Gao Yongshan, Wang Yun, Chen Longqi, Zhao Yongfan

机构信息

Department of Thoracic and Cardiovascular Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.

出版信息

Interact Cardiovasc Thorac Surg. 2011 Mar;12(3):366-9. doi: 10.1510/icvts.2010.258632. Epub 2010 Dec 24.

DOI:10.1510/icvts.2010.258632

PMID:21186282

Abstract

The aim was to compare the early outcomes between thoracoscopic and laparoscopic esophagectomy (TLE) and open three-field esophagectomy for esophageal cancer. We retrospectively analyzed clinical data from 96 patients with esophageal cancer who underwent TLE, and 78 patients who underwent open three-field esophagectomy from March 2008 to September 2010. All the operations were successful. There was no significant difference between TLE and open three-field esophagectomy with regard to the number of lymph nodes procured (17.75±5.56 vs. 18.03±6.20, P>0.05), complications (32.3% vs. 46.2%, P>0.05), and operative mortality (2.1% vs. 3.8%, P>0.05). However, hospital stay was significantly shorter in the TLE group than the open esophagectomy group (12.64±8.82 vs. 17.53±6.40 days, P<0.01), and the TLE group had significantly less blood loss (346.68±41.13 vs. 519.26±47.74 ml, P<0.01). This showed that TLE for esophageal cancer offers results as good as or better than those with open three-field esophagectomy.

摘要

本研究旨在比较胸腔镜与腹腔镜联合食管癌切除术（TLE）及开放性三野食管癌切除术治疗食管癌的早期疗效。我们回顾性分析了2008年3月至2010年9月期间96例行TLE的食管癌患者和78例行开放性三野食管癌切除术患者的临床资料。所有手术均成功。TLE与开放性三野食管癌切除术在获取淋巴结数量（17.75±5.56 vs. 18.03±6.20，P>0.05）、并发症发生率（32.3% vs. 46.2%，P>0.05）及手术死亡率（2.1% vs. 3.8%，P>0.05）方面无显著差异。然而，TLE组的住院时间明显短于开放性食管癌切除术组（12.64±8.82 vs. 17.53±6.40天，P<0.01），且TLE组的失血量明显较少（346.68±41.13 vs. 519.26±47.74 ml，P<0.01）。这表明食管癌TLE疗效与开放性三野食管癌切除术相当或更优。