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两种治疗牙本质过敏症方法的疗效比较:一项临床试验

Comparative efficacy of two treatment modalities for dentinal hypersensitivity: a clinical trial.

作者信息

Aparna S, Setty Swati, Thakur Srinath

机构信息

Department of Periodontics and Implantology, S.D.M. College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

出版信息

Indian J Dent Res. 2010 Oct-Dec;21(4):544-8. doi: 10.4103/0970-9290.74213.

Abstract

BACKGROUND

Dentin hypersensitivity is a recurrent condition causing discomfort and sometimes pain to the patient, which also deters him from maintaining adequate oral hygiene. Home care and office measures are used for treatment of this malady.

AIM

To evaluate and compare the efficacy of 2 treatment modalities for dentinal hypersensitivity, iontophoresis with acidulated phosphate gel (APF) gel, and dentin-bonding agent application.

MATERIALS AND METHODS

This split mouth randomized clinical study recruited subjects with a history of hypersensitivity with at least 2 teeth, verified by a light stroke with a dental explorer along the cervical third of the teeth. The patients were subjected to a 1-s air blast and cold water stimuli and their responses were recorded on a verbal rating scale. A total of 30 sites from 15 patients were divided into Group A-1.23% APF gel iontophoresis; and Group B-aqueous solution of hydroxyl-ethyl-methacrylate and glutaraldehyde. The teeth were evaluated immediately after the treatment and at the end of 2 weeks. In case of failure, the tooth was retreated with the same agent as before.

RESULTS

The results were statistically analyzed using Kruskal-Wallis analysis of variance and Mann-Whitney U tests. There was no statistically significant difference between the groups at the end of 2 weeks. However, Group A was more effective clinically, with fewer number of failures compared with Group B.

CONCLUSION

Both the agents showed a statistically significant reduction in sensitivity compared with baseline; however, APF gel iontophoresis was more effective in reducing hypersensitivity over a longer time period.

摘要

背景

牙本质过敏是一种反复发作的病症,会给患者带来不适,有时还会引起疼痛,这也使患者不愿保持良好的口腔卫生。家庭护理和诊所治疗措施都用于治疗这种疾病。

目的

评估和比较两种治疗牙本质过敏方法的疗效,即使用酸化磷酸氟(APF)凝胶进行离子导入和应用牙本质黏结剂。

材料与方法

这项双侧对照随机临床研究招募了有过敏史且至少有两颗牙齿的受试者,通过用牙科探针沿牙齿颈部三分之一处轻轻划动来确认。对患者进行1秒的气枪喷气和冷水刺激,并使用语言评定量表记录他们的反应。来自15名患者的总共30个部位被分为A组——1.23% APF凝胶离子导入;B组——甲基丙烯酸羟乙酯和戊二醛水溶液。治疗后立即以及在2周结束时对牙齿进行评估。如果治疗失败,用与之前相同的药物对牙齿进行再次治疗。

结果

使用Kruskal-Wallis方差分析和Mann-Whitney U检验对结果进行统计学分析。在2周结束时,两组之间没有统计学上的显著差异。然而,A组在临床上更有效,与B组相比失败病例数更少。

结论

与基线相比,两种药物的敏感性均有统计学上的显著降低;然而,APF凝胶离子导入在较长时间段内更有效地降低了过敏反应。

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