Andersson J K, Rybo G
Department of Obstetrics and Gynaecology, East Hospital, University of Göteborg, Sweden.
Br J Obstet Gynaecol. 1990 Aug;97(8):690-4. doi: 10.1111/j.1471-0528.1990.tb16240.x.
In 20 women with menorrhagia (greater than 80 ml blood loss per menstrual period) a levonorgestrel-releasing intrauterine device (Lng-IUCD) was inserted. Menstrual blood loss (MBL) was measured in two consecutive cycles before the device was inserted and after 3, 6 and 12 months of use. MBL was significantly reduced after 3 months (86%) and after 12 months the reduction was 97%. There was a significant increase (P less than 0.001) in serum ferritin during the first year of Lng-IUCD use. The Lng-IUCD seems to be an important alternative to oral medication and to hysterectomy in the treatment of menorrhagia.
在20名月经过多（每个月经周期失血超过80毫升）的女性中，插入了左炔诺孕酮宫内节育器（LNG-IUCD）。在插入该装置前以及使用3、6和12个月后，连续两个周期测量月经失血量（MBL）。3个月后MBL显著减少（86%），12个月后减少了97%。在使用LNG-IUCD的第一年，血清铁蛋白显著增加（P<0.001）。LNG-IUCD似乎是治疗月经过多的口服药物和子宫切除术的重要替代方法。
