In vitro RNA synthesis in nuclei from herpes simplex virus infected cells: effects of ultraviolet-irradiated, defective and bromodeoxyuridine-resistant virus preparations.

Transcription of virus DNA was detectable in vitro in nuclei isolated from cells infected with wild type and bromodeoxyuridine (BUdR)-resistant herpes simplex virus type 1 but was suppressed in nuclei of cells infected with ultraviolet irradiated or defective virus or cells treated with BUdR during infection.