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Synthesis of herpes simplex virus DNA in preparations of chromatin from infected cell nuclei.

作者信息

Hay R T, Hay J

出版信息

J Gen Virol. 1978 Nov;41(2):427-31. doi: 10.1099/0022-1317-41-2-427.

DOI:10.1099/0022-1317-41-2-427
PMID:214524
Abstract

Chromatin prepared from cells infected with Herpes simplex virus type 1 or type 2 can synthesize both virus and cell DNA in vitro. The rate of synthesis is comparable to that of isolated whole nuclei. Incorporation is limited, and both cell and virus DNA synthesis are sensitive to the presence of virus-specific antiserum and phosphonoacetate. In chromatin from cells infected with a phosphonoacetate resistant virus mutant, both types of DNA synthesis are resistant to the presence of the inhibitor.

摘要

相似文献

1
Synthesis of herpes simplex virus DNA in preparations of chromatin from infected cell nuclei.
J Gen Virol. 1978 Nov;41(2):427-31. doi: 10.1099/0022-1317-41-2-427.
2
In vitro synthesis of herpes simplex virus DNA in nuclei isolated from infected BSC 1 cells.从感染的BSC 1细胞中分离出的细胞核内单纯疱疹病毒DNA的体外合成。
J Gen Virol. 1977 Feb;34(2):223-34. doi: 10.1099/0022-1317-34-2-223.
3
Effect of herpes simplex virus type 1 infection on the cellular DNA polymerase activities of mouse cell cultures.
J Gen Virol. 1978 Dec;41(3):479-91. doi: 10.1099/0022-1317-41-3-479.
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Synthesis of herpes simplex virus, vaccinia virus, and adenovirus DNA in isolated HeLa cell nuclei. I. Effect of viral-specific antisera and phosphonoacetic acid.单纯疱疹病毒、痘苗病毒和腺病毒DNA在离体HeLa细胞核中的合成。I. 病毒特异性抗血清和膦甲酸的作用。
J Virol. 1975 Dec;16(6):1584-92. doi: 10.1128/JVI.16.6.1584-1592.1975.
5
Characteristics of herpes simplex virus resistance to disodium phosphonoacetate.单纯疱疹病毒对膦甲酸钠耐药的特征。
Intervirology. 1978;9(4):193-205. doi: 10.1159/000148937.
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The effect of triterpenoid compounds on uninfected and herpes simplex virus-infected cells in culture. II. DNA and protein synthesis, polypeptide processing and transport.三萜类化合物对培养中的未感染细胞和单纯疱疹病毒感染细胞的影响。II. DNA和蛋白质合成、多肽加工与转运。
J Gen Virol. 1986 Sep;67 ( Pt 9):1831-50. doi: 10.1099/0022-1317-67-9-1831.
7
Mutants of herpes simplex virus types 1 and 2 that are resistant to phosphonoacetic acid induce altered DNA polymerase activities in infected cells.对膦甲酸具有抗性的1型和2型单纯疱疹病毒突变体在受感染细胞中诱导出改变的DNA聚合酶活性。
J Gen Virol. 1976 Apr;31(1):145-8. doi: 10.1099/0022-1317-31-1-145.
8
Synthesis of viral and host DNA in isolated chromatin from herpes simplex virus-infected HeLa cells.单纯疱疹病毒感染的HeLa细胞中分离染色质内病毒和宿主DNA的合成
J Virol. 1978 May;26(2):281-90. doi: 10.1128/JVI.26.2.281-290.1978.
9
Phosphonoacetic acid-resistant mutants of herpes simplex virus: effect of phosphonoacetic acid on virus replication and in vitro deoxyribonucleic acid synthesis in isolated nuclei.单纯疱疹病毒的膦甲酸钠抗性突变体：膦甲酸钠对病毒复制及分离细胞核中体外脱氧核糖核酸合成的影响
Antimicrob Agents Chemother. 1977 May;11(5):919-22. doi: 10.1128/AAC.11.5.919.
10
[DNA synthesis in isolated nuclei and mitochondria from HeLa cells infected by Herpes simplex virus].[单纯疱疹病毒感染的HeLa细胞核与线粒体中的DNA合成]
Zentralbl Bakteriol Orig A. 1974;227(1-4):345-7.

引用本文的文献

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Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes.三聚基序蛋白22（TRIM22）通过对病毒立即早期基因进行表观遗传沉默来限制单纯疱疹病毒1。
PLoS Pathog. 2021 Feb 1;17(2):e1009281. doi: 10.1371/journal.ppat.1009281. eCollection 2021 Feb.
2
Replication of herpes simplex virus type I DNA in permeabilized infected cells.单纯疱疹病毒I型DNA在经通透处理的感染细胞中的复制。
Nucleic Acids Res. 1980 Apr 11;8(7):1661-73. doi: 10.1093/nar/8.7.1661.
3
DNA synthesis in chromatin preparations from human fibroblasts infected by cytomegalovirus.
巨细胞病毒感染的人成纤维细胞染色质制剂中的DNA合成。
Arch Virol. 1980;65(1):45-51. doi: 10.1007/BF01340539.
4
Inhibition of cellular and virus-associated nucleotide polymerases by, and anti-herpes simplex virus activity of, streptovaricin derivatives.链黑菌素衍生物对细胞和病毒相关核苷酸聚合酶的抑制作用及其抗单纯疱疹病毒活性
Antimicrob Agents Chemother. 1981 Nov;20(5):653-9. doi: 10.1128/AAC.20.5.653.