蝙蝠和病毒。
Bat and virus.
机构信息
State key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
出版信息
Protein Cell. 2010 Feb;1(2):109-14. doi: 10.1007/s13238-010-0029-7.
Abstract
Bat, the only flying mammal and count more than 20% of the extant mammals on earth, were recently identified as a natural reservoir of emerging and reemerging infectious pathogens. Astonishing amount (more than 70) and genetic diversity of viruses isolated from the bat have been identified in different populations throughout the world. Many studies focus on bat viruses that caused severe domestic and human diseases. However, many viruses were found in apparently healthy bats, suggesting that bats may have a specific immune system or antiviral activity against virus infections. Therefore, basic researches for bat immunology and virus-host interactions are important for understanding bat-derived infectious diseases.
摘要
蝙蝠是唯一会飞的哺乳动物，占地球上现存哺乳动物的 20%以上，最近被确定为新兴和再现传染病原体的自然宿主。从世界各地不同种群的蝙蝠中分离出的病毒数量惊人（超过 70 种），且具有遗传多样性。许多研究集中在导致严重家畜和人类疾病的蝙蝠病毒上。然而，在明显健康的蝙蝠中也发现了许多病毒，这表明蝙蝠可能具有针对病毒感染的特定免疫系统或抗病毒活性。因此，蝙蝠免疫学和病毒-宿主相互作用的基础研究对于了解蝙蝠源性传染病非常重要。
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