Valiante N M, Caton A J
Wistar Institute of Anatomy and Biology, Philadelphia, PA 19104.
Immunogenetics. 1990;32(5):345-50. doi: 10.1007/BF00211649.
We have identified and characterized a novel mouse Igk-V gene family, which we have designated Igk-V34. Southern hybridization and nucleotide sequence analysis indicate that this family is comprised of either one or two members in mice of different Igk haplotypes. The gene family members share between 95% and 98% sequence similarity, indicating that they diverged only recently during the evolution of the Igk locus. Sequence relationships between members of this family are discussed.
我们已经鉴定并描述了一个新的小鼠Igk-V基因家族，我们将其命名为Igk-V34。Southern杂交和核苷酸序列分析表明，在不同Igk单倍型的小鼠中，这个家族由一个或两个成员组成。该基因家族成员的序列相似度在95%到98%之间，这表明它们在Igk基因座的进化过程中是最近才分化的。本文讨论了该家族成员之间的序列关系。
