Instituto de Quimica, Universidade Estadual Paulista, Araraquara, SP, Brazil.
Nat Prod Res. 2011 Jan;25(1):1-7. doi: 10.1080/14786410903244954.
A phytochemical investigation of the leaves and stems of Peperomia obtusifolia (Piperaceae) yielded a new flavone C-diglycoside isoswertisin-4'-methyl-ether-2''α-L-rhamnoside (1), along with four known compounds: isoswertisin-2''α-L-rhamnoside (2), (+)-diayangambin (3), 2-episesalatin (4) and corchoionoside C (5). The structures of the two flavone C-diglycosides (1, 2) were elucidated on the basis of 1D and 2D NMR spectroscopy and MS spectrometric data. These flavones were evaluated by bioautographic assay against Cladosporium cladosporioides and C. sphaerospermum and showed weak antifungal activity.
对胡椒科梨果胡椒（Peperomia obtusifolia）的叶和茎进行的植物化学研究得到了一个新的类黄酮 C-二糖苷异牡荆素-4'-甲基醚-2''α-L-鼠李糖苷（1），以及四个已知化合物：异牡荆素-2''α-L-鼠李糖苷（2）、（+）-二杨氨宾（3）、2-表芝麻素（4）和桑辛素 C（5）。基于 1D 和 2D NMR 光谱和 MS 光谱数据，确定了这两种类黄酮 C-二糖苷（1、2）的结构。通过生物自显影法对梨果胡椒叶和茎的提取物进行了抗炭疽菌属（Cladosporium cladosporioides 和 C. sphaerospermum）活性测试，结果显示出较弱的抗真菌活性。
