Lago João Henrique G, Ramos Clécio Sousa, Casanova Diego Campos C, Morandim Andreia de A, Bergamo Debora Cristina B, Cavalheiro Alberto J, Bolzani Vanderlan da S, Furlan Maysa, Guimarães Elsie F, Young Maria Claudia M, Kato Massuo J
Instituto de Química, Universidade de São Paulo, C.P. 26077-05599-970, São Paulo, SP, Brazil.
J Nat Prod. 2004 Nov;67(11):1783-8. doi: 10.1021/np030530j.
Piper crassinervium, P. aduncum, P. hostmannianum, and P. gaudichaudianum contain the new benzoic acid derivatives crassinervic acid (1), aduncumene (8), hostmaniane (18), and gaudichaudianic acid (20), respectively, as major secondary metabolites. Additionally, 19 known compounds such as benzoic acids, chromenes, and flavonoids were isolated and identified. The antifungal activity of these compounds was evaluated by bioautographic TLC assay against Cladosporium cladosporioides and C. sphaerospermum.
厚脉胡椒、歪叶胡椒、霍氏胡椒和高迪胡椒分别含有新的苯甲酸衍生物厚脉胡椒酸（1）、歪叶胡椒烯（8）、霍氏胡椒烷（18）和高迪胡椒酸（20）作为主要次生代谢产物。此外，还分离并鉴定了19种已知化合物，如苯甲酸、色烯和黄酮类化合物。通过生物自显影薄层色谱法对这些化合物针对枝孢霉和球孢枝孢的抗真菌活性进行了评估。
