Gallego Lorena, García-Consuegra Luis, Fuente Eduardo, Calvo Nicolás, Junquera Luis
University of Oviedo Dental School, Spain.
J Med Case Rep. 2011 Jan 17;5:11. doi: 10.1186/1752-1947-5-11.
Oncocytic carcinoma is a rare proliferation of cytomorphologically malignant oncocytes mainly found in glandular tissue, accounting for 0.5% of all epithelial salivary gland malignancies and 0.18% of all epithelial salivary gland tumors.
We report a case of oncocytic carcinoma arising in the parotid gland of a 65-year-old Caucasian man. Our patient initially underwent left superficial parotidectomy, including the removal of the mass. A close follow-up was made, and four years after first surgery cervical lymph node metastases were confirmed. Therefore, a complete parotidectomy and radical neck dissections were performed. There were no complications and no sign of recurrence after six months of follow-up.
Oncocytic carcinoma is an extremely rare malignancy in the salivary glands. Prophylactic neck dissection may be indicated for tumors larger than 2 cm in diameter (our patient's tumor was 2.5 cm at its greatest diameter). The clinical course of our patient, with the appearance of cervical lymph node metastases after four years of follow-up, supports this approach. Further investigation of the prognosis and correct treatment of patients with oncocytic carcinoma are required as more cases are reported.
嗜酸细胞癌是一种罕见的、细胞形态学上呈恶性的嗜酸细胞增殖性疾病，主要发生于腺组织，占所有涎腺上皮性恶性肿瘤的0.5%，占所有涎腺上皮性肿瘤的0.18%。
我们报告一例发生于一名65岁白种男性腮腺的嗜酸细胞癌。患者最初接受了左侧腮腺浅叶切除术，包括肿物切除。进行了密切随访，首次手术后四年证实出现颈部淋巴结转移。因此，进行了全腮腺切除术和根治性颈清扫术。随访六个月后无并发症且无复发迹象。
嗜酸细胞癌是涎腺中极为罕见的恶性肿瘤。对于直径大于2 cm的肿瘤（我们患者的肿瘤最大直径为2.5 cm）可能需要进行预防性颈清扫术。我们患者在随访四年后出现颈部淋巴结转移的临床过程支持了这种方法。随着更多病例的报告，需要对嗜酸细胞癌患者的预后和正确治疗进行进一步研究。
