Department of Phytochemistry and Plant Systematics, National Research Centre, Dokki-Giza 12622, Egypt.
Nat Prod Res. 2011 Jan;25(2):141-51. doi: 10.1080/14786419.2010.518146.
In this study, extracts of the flowers of the folk medicinal plant Bombax malabaricum DC were biologically and chemically screened. Chemical constituents in the n-hexane fraction from the flowers of B. malabaricum DC were investigated using gas-liquid chromatography (GLC) analysis, affording 14 compounds, including cholesterol, stigmasterol, campesterol and α-amyrin, while the residual 10 compounds are hydrocarbons. GLC analysis of the fatty acid (FA) esters established the majority abundance of the saturated FA over their unsaturated analogues. The polar methanol fraction afforded seven flavones: vicenin 2 (1), linarin (2), saponarin (3), cosmetin (4), isovitexin (5), xanthomicrol (6) and apigenin (7). Structures 1-7 were established by intensive studies of various spectral data (H-NMR, mass spectroscopy and UV) and comparison with authentic samples. Compounds 1-7 are described here for the first time from this plant. Extracts of n-hexane and methanol exhibited significant antioxidant and antimicrobial activities.
在这项研究中，对民间药用植物黄花木的花朵提取物进行了生物和化学筛选。采用气相色谱（GLC）分析研究了黄花木花朵的正己烷馏分中的化学成分，得到了 14 种化合物，包括胆固醇、豆甾醇、菜油甾醇和α-香树脂醇，而其余 10 种化合物为烃类。脂肪酸（FA）酯的 GLC 分析确定了饱和 FA 比其不饱和类似物更为丰富。极性甲醇馏分中得到了七种黄酮类化合物：vicenin 2（1）、linarin（2）、saponarin（3）、cosmetin（4）、isovitexin（5）、xanthomicrol（6）和apigenin（7）。通过各种光谱数据（H-NMR、质谱和 UV）的深入研究以及与标准样品的比较，确定了化合物 1-7 的结构。化合物 1-7 是首次从该植物中分离得到的。正己烷和甲醇提取物表现出显著的抗氧化和抗菌活性。
