Department of Operative and Preventive Dentistry & Periodontology, RWTH Aachen University Hospital, Germany.
Archaea. 2010 Dec 30;2010:967271. doi: 10.1155/2010/967271.
The human body (primarily the intestinal tract, the oral cavity, and the skin) harbours approximately 1,000 different bacterial species. However, the number of archaeal species known to colonize man seems to be confined to a handful of organisms within the class Euryarchaeota (including Methanobrevibacter smithii, M. oralis, and Methanosphaera stadtmanae). In contrast to this conspicuously low diversity of Archaea in humans their unique physiology in conjunction with the growing number of reports regarding their occurrence at sites of infection has made this issue an emerging field of study. While previous review articles in recent years have addressed the putative role of particularly methanogenic archaea for human health and disease, this paper compiles novel experimental data that have been reported since then. The aim of this paper is to inspire the scientific community of "Archaea experts" for those unique archaeal organisms that have successfully participated in the human-microbe coevolution.
人体（主要是肠道、口腔和皮肤）中大约栖息着 1000 种不同的细菌物种。然而，已知定植于人体的古菌物种数量似乎仅限于少数几个广古菌门（Euryarchaeota）的生物（包括产甲烷短杆菌（Methanobrevibacter smithii）、口腔甲烷短杆菌（M. oralis）和史氏甲烷八叠球菌（Methanosphaera stadtmanae））。与人体中明显较低多样性的古菌形成鲜明对比的是，它们独特的生理学特性以及越来越多的关于它们在感染部位存在的报告，使这一问题成为一个新兴的研究领域。虽然近年来的一些综述文章已经探讨了特定产甲烷古菌对人类健康和疾病的潜在作用，但本文汇编了自那时以来报告的新的实验数据。本文的目的是激发“古菌专家”科学界的兴趣，关注那些成功参与人类-微生物共同进化的独特古菌生物。
