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老年人群中痴呆症的患病率不断增加。

Increasing prevalence of dementia among very old people.

机构信息

Geriatric Medicine, Department of Community Medicine and Rehabilitation, Umeå University, Umeå SE-901 85, Sweden.

出版信息

Age Ageing. 2011 Mar;40(2):243-9. doi: 10.1093/ageing/afq173. Epub 2011 Jan 22.

Abstract

BACKGROUND

it is unknown whether the age-specific prevalence of dementia among the very old changes over time.

METHODS

this study compares the prevalence of dementia in two population-based cross-sectional samples of very old people in northern Sweden in 2000-02 and in 2005-07. In total, 430 individuals aged 85 and older (mean age 89.5 years, 71.4% women) were evaluated for dementia in the first cross-section and 465 individuals (mean age 90.2 years, 70.9% women) in the second. Trained assessors performed assessments and interviews during home visits and collected information from carers, relatives and medical records. Dementia was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria.

RESULTS

the prevalence of dementia in the total sample was 26.5% in 2000-02 and 37.2% in 2005-07 (P = 0.001). There was also an increase in the prescription of different antihypertensive agents, antilipemic agents and choline esterase inhibitors, and more people had had heart surgery in the later sample.

CONCLUSIONS

in this sample of very old people, an increase in the age-specific prevalence of dementia was detected over 5 years. Possible reasons for this may be extended survival among individuals with risk factors for dementia and among individuals with established dementia.

摘要

背景

尚不清楚超高龄人群中特定年龄组的痴呆患病率是否随时间而变化。

方法

本研究比较了瑞典北部 2000-02 年和 2005-07 年两个基于人群的超高龄人群横断面样本中痴呆的患病率。共有 430 名 85 岁及以上(平均年龄 89.5 岁,71.4%为女性)的个体在第一次横断面研究中接受痴呆评估,465 名(平均年龄 90.2 岁,70.9%为女性)在第二次横断面研究中接受评估。经过培训的评估员在家庭访视中进行评估和访谈,并从护理人员、亲属和医疗记录中收集信息。痴呆症的诊断依据是《精神障碍诊断与统计手册》第四版标准。

结果

2000-02 年总样本中痴呆的患病率为 26.5%,2005-07 年为 37.2%(P = 0.001)。在后来的样本中,不同抗高血压药物、降脂药物和胆碱酯酶抑制剂的处方也有所增加,更多的人接受了心脏手术。

结论

在这个超高龄人群样本中,在 5 年内检测到特定年龄组的痴呆患病率增加。这种情况的可能原因是痴呆风险因素人群和确诊痴呆人群的生存时间延长。

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