基于壳聚糖和壳聚糖的生物材料在创伤敷料中的应用。

Biomaterials based on chitin and chitosan in wound dressing applications.

机构信息

Amrita Centre for Nanosciences and Molecular Medicine, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidhyapeetham University, Cochin-682041, India.

出版信息

Biotechnol Adv. 2011 May-Jun;29(3):322-37. doi: 10.1016/j.biotechadv.2011.01.005. Epub 2011 Jan 22.

DOI:10.1016/j.biotechadv.2011.01.005

PMID:21262336

Abstract

Wound dressing is one of the most promising medical applications for chitin and chitosan. The adhesive nature of chitin and chitosan, together with their antifungal and bactericidal character, and their permeability to oxygen, is a very important property associated with the treatment of wounds and burns. Different derivatives of chitin and chitosan have been prepared for this purpose in the form of hydrogels, fibers, membranes, scaffolds and sponges. The purpose of this review is to take a closer look on the wound dressing applications of biomaterials based on chitin, chitosan and their derivatives in various forms in detail.

摘要

伤口敷料是甲壳素和壳聚糖最有前途的医学应用之一。甲壳素和壳聚糖的粘性，以及它们的抗真菌和杀菌特性，和它们对氧气的通透性，是与伤口和烧伤治疗相关的非常重要的特性。为了达到这个目的，不同形式的甲壳素和壳聚糖的衍生物被制备成水凝胶、纤维、膜、支架和海绵。本文的目的是详细探讨各种形式的基于甲壳素、壳聚糖及其衍生物的生物材料在伤口敷料方面的应用。