Vaneechoutte M, Verschraegen G, Claeys G, Weise B, Van den Abeele A M
Laboratory for Bacteriology and Virology, University Hospital, Ghent, Belgium.
J Clin Microbiol. 1990 Dec;28(12):2674-80. doi: 10.1128/jcm.28.12.2674-2680.1990.
Nonselective media and previously described selective media were used to study the occurrence of Moraxella (Branhamella) catarrhalis in sputum samples of good and poor quality and in samples taken from different sites of the upper respiratory tracts of healthy subjects. It was found that in healthy adults the carrier rate was 5.4%, as opposed to 50.8% in children and 26.5% in people older than 60 years. M. catarrhalis was recovered significantly more often from sputum samples of good quality (5%) than from poor quality samples (0.5%), and when present, it was found mostly in the presence of high inocula. From these data gathered from healthy and diseased subjects, it is concluded that the presence of M. catarrhalis in the sputum of adults is rarely due to oronasopharyngeal contamination of the sputum. Similar findings reported by others are discussed, and the origins of the currently held concept that M. catarrhalis is a common commensal organism of the human upper respiratory tract are traced.
使用非选择性培养基和先前描述的选择性培养基，研究了卡他莫拉菌（布兰汉菌属）在质量好与质量差的痰液样本以及健康受试者上呼吸道不同部位采集的样本中的出现情况。结果发现，健康成年人的携带率为5.4%，而儿童为50.8%，60岁以上人群为26.5%。从质量好的痰液样本（5%）中分离出卡他莫拉菌的频率明显高于质量差的样本（0.5%），而且当存在该菌时，大多是在接种量大的情况下发现的。根据从健康和患病受试者收集的这些数据得出结论，成年人痰液中卡他莫拉菌的存在很少是由于痰液的口鼻咽部污染所致。讨论了其他人报告的类似发现，并追溯了目前认为卡他莫拉菌是人类上呼吸道常见共生菌这一概念的起源。
