Hoeppner V H, Ring E D
Can Fam Physician. 1987 May;33:1231-5.
Caucasian Canadians are in the tertiary phase of a 300-year tuberculosis epidemic. In this phase, the pattern of disease over the age spectrum is low in the young and middle-aged groups and rises to four times this rate in the elderly. The concentration of the elderly in chronic care homes (CCHs) magnifies the tuberculosis problem by increasing case rates another four times above the rate of elderly persons living separately, and 20 times above the overall Canadian rate. In spite of effective drugs with cure rates of over 95%, tuberculosis in the institutionalized elderly continues at an alarming rate. The difficulty lies in case finding. The prevailing attitude is that tuberculosis is no longer a problem. Surveillance programs are rudimentary. Between 35% and 40% of active cases in CCHs are the result of primary infection, mimicking bacterial pneumonia clinically and radiographically. In this target group of high-incidence tuberculosis, surveillance of residents is necessary, and the diagnosis needs to be considered in antibiotic-unresponsive pneumonia and in fever of unknown origin.
加拿大白人正处于一场持续300年的结核病流行的第三阶段。在这个阶段,各年龄段的疾病模式是,青年和中年群体发病率较低,而老年人的发病率则升至该比率的四倍。老年人集中在慢性护理院(CCHs),使得结核病问题更加严重,其发病率比独居老年人高出四倍,比加拿大总体发病率高出20倍。尽管有治愈率超过95%的有效药物,但机构养老的老年人中的结核病发病率仍居高不下。困难在于病例发现。普遍的态度是结核病不再是一个问题。监测项目很不完善。慢性护理院35%至40%的活动性病例是原发性感染的结果,在临床和影像学上类似于细菌性肺炎。在这个结核病高发的目标群体中,对居民进行监测是必要的,对于抗生素治疗无效的肺炎和不明原因发热需要考虑结核病的诊断。