Carter C J
Can Fam Physician. 1987 Nov;33:2557-60.
The author describes the clinical rationale and pharmacology of current anticoagulant therapy. He goes on to discuss the intensity of therapy by means of oral anticoagulants, the means of monitoring this therapy, and the standardization of monitoring procedures. He also describes the indications for and best means of administering and monitoring heparin therapy, together with the major clinical indications for both heparin and oral anticoagulant therapy.
作者描述了当前抗凝治疗的临床基本原理和药理学。他接着讨论了通过口服抗凝剂进行治疗的强度、监测该治疗的方法以及监测程序的标准化。他还描述了肝素治疗的适应证、给药和监测的最佳方法,以及肝素和口服抗凝剂治疗的主要临床适应证。