How does interferon-α insult the vasculature? Let me count the ways.
作者信息
Kaplan Mariana J, Salmon Jane E
出版信息
Arthritis Rheum. 2011 Feb;63(2):334-6. doi: 10.1002/art.30161.
Abstract
摘要
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How does interferon-α insult the vasculature? Let me count the ways.α干扰素是如何损害脉管系统的？让我来细数一下。
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Sci Transl Med. 2010 Sep 1;2(47):47ra63. doi: 10.1126/scitranslmed.3001001.
2
The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction.干扰素-α对狼疮血管生成的有害作用是通过抑制白细胞介素-1途径介导的：在动脉粥样硬化和肾血管稀疏中的潜在作用。
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3
Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.系统性红斑狼疮患者的血小板转录谱和蛋白表达：I 型干扰素系统的上调与血管疾病强烈相关。
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Lupus-prone New Zealand Black/New Zealand White F1 mice display endothelial dysfunction and abnormal phenotype and function of endothelial progenitor cells.狼疮易感型新西兰黑/新西兰白 F1 小鼠表现出内皮功能障碍和内皮祖细胞的异常表型和功能。
Lupus. 2010 Mar;19(3):288-99. doi: 10.1177/0961203309353773. Epub 2010 Jan 12.
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Nat Rev Immunol. 2010 Jan;10(1):36-46. doi: 10.1038/nri2675. Epub 2009 Dec 4.
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Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus.在系统性红斑狼疮患者中进行的一项抗干扰素-α单克隆抗体I期试验中，干扰素-α/β诱导基因的中和作用及下游效应
Arthritis Rheum. 2009 Jun;60(6):1785-96. doi: 10.1002/art.24557.
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Immunol Rev. 2008 Jun;223:271-83. doi: 10.1111/j.1600-065X.2008.00630.x.
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Circulation. 2007 Oct 30;116(18):2043-52. doi: 10.1161/CIRCULATIONAHA.107.697789. Epub 2007 Oct 15.
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