Cell and Molecular Biology Division, Department of Botany, University of Calicut, Calicut, Kerala, India.
Pharm Biol. 2011 May;49(5):456-63. doi: 10.3109/13880209.2010.523427. Epub 2011 Feb 2.
Vector control is facing a threat due to the emergence of resistance to synthetic insecticides. In this context, essential oils have received much attention as potentially useful bioactive compounds against insects. Therefore, our present study aimed to evaluate the efficacy of essential oils from the aerial parts of Salvia elegans Vahl, Salvia dorisiana Standl., Salvia splendens Sello ex J.A. Schult Blue Ribbon, and S. splendens Sello ex J.A. Schult Scarlet Sage Red (Lamiaceae) against the fourth instar larvae of Aedes albopictus Skuse (Diptera: Culicidae).
The mosquito larvicidal activities of the essential oils and chemical composition of four taxa of Salvia are investigated in this article for the first time.
Chemical compositions of essential oils obtained from four taxa of Salvia were analyzed by gas chromatography-mass spectrometry (GC-MS), GC-FID, and the effects of essential oils on fourth instar larvae of A. albopictus were investigated.
The main components identified from each Salvia essential oils were as follows: spathulenol (38.73%) and caryophyllene (10.32%) from S. elegans; ledol (45.8%) and 4,4'-[(p-phenylene)diisopropylidene]diphenol (17.38%) from S. dorisiana; β-cubebene (22.9%), and caryophyllene (12.99%) from S. splendens Blue Ribbon; phytol (41.46%) and cyclooctasulfur (24.88%) from S. splendens Scarlet Sage Red. The essential oils of S. elegans and S. splendens Blue Ribbon had excellent inhibitory larvicidal effect against A. albopictus larvae, and their LC(50) values in 24 h were 46.4 ppm (LC(90) = 121.8 ppm) and 59.2 ppm (LC(90) = 133.0 ppm), respectively.
These findings demonstrate that the essential oils of these Salvia species could be considered as the powerful candidates to bring about useful botanicals so as to prevent the resurgence of mosquito vectors.
由于对合成杀虫剂产生抗药性，病媒控制正面临威胁。在这种情况下，精油作为对抗昆虫的潜在有用生物活性化合物受到了广泛关注。因此，本研究旨在评估 Salvia elegans Vahl、Salvia dorisiana Standl.、Salvia splendens Sello ex J.A. Schult Blue Ribbon 和 S. splendens Sello ex J.A. Schult Scarlet Sage Red（唇形科）植物挥发油对致倦库蚊第四龄幼虫的杀虫活性。
首次研究了这 4 种 Salvia 植物挥发油的蚊虫幼虫毒杀活性及其化学成分。
采用气相色谱-质谱联用（GC-MS）、GC-FID 分析 4 种 Salvia 植物挥发油的化学成分，并研究其对致倦库蚊第四龄幼虫的影响。
从每种 Salvia 植物挥发油中鉴定出的主要成分如下：S. elegans 的蛇床烯（38.73%）和石竹烯（10.32%）；S. dorisiana 的 Ledol（45.8%）和 4,4'-[(对苯二亚甲基)二异丙基]二苯酚（17.38%）；S. splendens Blue Ribbon 的β-古巴烯（22.9%）和石竹烯（12.99%）；S. splendens Scarlet Sage Red 的植醇（41.46%）和环辛四硫醚（24.88%）。S. elegans 和 S. splendens Blue Ribbon 的挥发油对致倦库蚊幼虫具有优异的抑制杀虫效果，其 24 小时半数致死浓度（LC50）分别为 46.4 ppm（LC90 = 121.8 ppm）和 59.2 ppm（LC90 = 133.0 ppm）。
这些发现表明，这些 Salvia 物种的挥发油可被视为有潜力的候选物，以带来有用的植物学方法，从而防止蚊虫媒介的死灰复燃。
