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银屑病患者的健康相关生活质量。

Health-related quality of life in patients with psoriasis.

机构信息

The Institute of Epidemiology, School of Medicine, Universtity of Belgrade, Serbia.

出版信息

J Cutan Med Surg. 2011 Jan-Feb;15(1):29-36. doi: 10.2310/7750.2010.10009.

DOI:10.2310/7750.2010.10009
PMID:21291653
Abstract

BACKGROUND

Psoriasis is a chronic skin disease that has a significant impact on patients' lives.

OBJECTIVE

The purpose of the study was to assess factors that might influence the health-related quality of life (HRQoL) of patients with psoriasis.

METHODS

We conducted a cross-sectional study of 110 outpatients with psoriasis. To assess the HRQoL, The Short Form 36 Health Survey (SF-36) and Skindex-29 were administered. Stressful life events during the last 12 months were assessed with Paykel's Interview for Recent Life Events.

RESULTS

HRQoL was significantly more impaired in older patients, those with age at onset of 40 years or more, who had a positive family history and who experienced stressful life events in the 12 months preceding the interview. Sex and clinical severity were not significantly related to patients' HRQoL.

CONCLUSION

Psoriasis patients have poorer HRQoL than the general population. This study supports the decision to use both generic and skin-specific instruments to assess the impact of psoriasis on HRQoL.

摘要

背景

银屑病是一种慢性皮肤病,对患者的生活有重大影响。

目的

本研究旨在评估可能影响银屑病患者健康相关生活质量(HRQoL)的因素。

方法

我们对 110 名门诊银屑病患者进行了横断面研究。为了评估 HRQoL,我们使用了 36 项简短健康调查(SF-36)和 Skindex-29 量表。在过去 12 个月中,使用 Paykel 的近期生活事件访谈评估了应激性生活事件。

结果

年龄较大、发病年龄在 40 岁及以上、有阳性家族史和在访谈前 12 个月经历应激性生活事件的患者,其 HRQoL 显著受损。性别和临床严重程度与患者的 HRQoL 无显著相关性。

结论

银屑病患者的 HRQoL 比一般人群差。本研究支持使用通用和皮肤特异性工具来评估银屑病对 HRQoL 的影响的决定。

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