洋葱伯克霍尔德菌原生质体和全细胞对多粘菌素B的抗性
Resistance of spheroplasts and whole cells of Pseudomonas cepacia to polymyxin B.
作者信息
Manniello J M, Heymann H, Adair F W
出版信息
Antimicrob Agents Chemother. 1978 Sep;14(3):500-4. doi: 10.1128/AAC.14.3.500.
Abstract
Sucrose-lysozyme spheroplasts were prepared from two strains of Pseudomonas cepacia and tested for susceptibility to polymyxin B and benzalkonium chloride. Spheroplasts were more susceptible than whole cells to benzalkonium chloride but not to polymyxin B. Disruption of the outer membrane layer was not by itself sufficient to render P. cepacia susceptible to polymyxin B.
摘要
从洋葱伯克霍尔德菌的两株菌株制备了蔗糖 - 溶菌酶原生质球，并测试了它们对多粘菌素B和苯扎氯铵的敏感性。原生质球比完整细胞对苯扎氯铵更敏感，但对多粘菌素B不敏感。外膜层的破坏本身不足以使洋葱伯克霍尔德菌对多粘菌素B敏感。
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