西班牙首例移植受者中微孢子虫病病例及文献复习
First cases of microsporidiosis in transplant recipients in Spain and review of the literature.
机构信息
Laboratorio de Parasitología, Facultad de Farmacia, Universidad San Pablo-CEU, Urbanización Montepríncipe, 28668 Boadilla del Monte, Madrid, Spain.
出版信息
J Clin Microbiol. 2011 Apr;49(4):1301-6. doi: 10.1128/JCM.01833-10. Epub 2011 Feb 16.
Abstract
Microsporidia are currently considered emerging pathogens responsible for life-threatening infections in organ transplant recipients. Here, we describe the first cases of intestinal microsporidiosis by Enterocytozoon bieneusi genotype D in two non-HIV-infected renal transplant recipients from Spain. Previously reported cases of microsporidiosis in organ transplant recipients have also been reviewed, highlighting the necessity of considering organ transplant recipients a risk group for microsporidiosis. A systematic search for these parasites is recommended in cases of persistent diarrhea and in the differential diagnosis of other syndromes, such as chronic fever of unknown etiology.
摘要
微孢子虫目前被认为是新兴的病原体，可导致器官移植受者发生危及生命的感染。在此，我们描述了两例来自西班牙的非 HIV 感染的肾移植受者发生肠微孢子虫病（由肠细胞艾美耳球虫基因型 D 引起）的首例病例。我们还回顾了先前报道的器官移植受者中的微孢子虫病病例，强调有必要将器官移植受者视为微孢子虫病的一个风险群体。建议在持续性腹泻以及其他综合征（如不明原因的慢性发热）的鉴别诊断中，对这些寄生虫进行系统搜索。
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