Elder Charles, Mossbrucker Pat, Davino-Ramaya Carrie M, Bez Ileana, Lin Margaret M, Terry Theresa A, Thomas Emily A, Jones Sean
Perm J. 2008 Summer;12(3):52-8. doi: 10.7812/TPP/07-146.
Herbal and other dietary supplements are popular among patients. Whether and how to establish and manage an herbal formulary remains a challenge for conventional managed-care organizations. Pharmacists and clinicians depend on evidence-based guidelines to help determine which products (whether pharmaceutical or herbal) to make available to patients. Evidence from randomized controlled trials that supports the use of most herbal supplements is scarce, yet for some supplements, credible evidence supports the possibility of efficacy. Quality control remains of concern for the supplement industry and for patients and clinicians considering the use of supplements.Clinicians may improve care by both disseminating educational materials and making available to patients popular quality-controlled herbal supplements deemed safe and effective. Kaiser Permanente Northwest (KPNW) has adopted a comprehensive and systematic approach to managing and stocking herbal supplements that can serve as a model for other conventional and managed care organizations.KPNW's dedicated Natural Products Advisory Committee (NPAC) has made considerable progress toward developing a constructive response to KPNW patients' herbal supplement use. Making supplements available at pharmacies can improve clinical outcomes, patient convenience, and quality control. NPAC currently limits its reviews to randomized, controlled trials and data from meta-analyses and systematic reviews for single-ingredient supplements. As interest in this area maintains steady growth, NPAC will continue to study how best to meet patients' needs.
草药及其他膳食补充剂在患者中很受欢迎。对于传统的管理式医疗组织而言,是否以及如何建立和管理草药配方仍然是一项挑战。药剂师和临床医生依靠循证指南来帮助确定向患者提供哪些产品(无论是药品还是草药)。支持使用大多数草药补充剂的随机对照试验证据很少,但对于一些补充剂,可靠的证据支持其具有疗效的可能性。补充剂行业以及考虑使用补充剂的患者和临床医生仍对质量控制感到担忧。临床医生可以通过分发教育材料以及向患者提供被认为安全有效的流行的质量受控草药补充剂来改善护理。凯撒永久医疗集团西北分部(KPNW)采用了一种全面而系统的方法来管理和储备草药补充剂,可为其他传统和管理式医疗组织树立榜样。KPNW专门的天然产品咨询委员会(NPAC)在对KPNW患者使用草药补充剂制定建设性应对措施方面取得了相当大的进展。在药房提供补充剂可以改善临床结果、方便患者并加强质量控制。NPAC目前将其审查限于单成分补充剂的随机对照试验以及荟萃分析和系统评价的数据。随着对该领域的兴趣持续稳定增长,NPAC将继续研究如何最好地满足患者需求。