夏威夷主要为汤加人的人群中传统卡瓦饮料的消费情况及肝功能测试

Traditional kava beverage consumption and liver function tests in a predominantly Tongan population in Hawaii.

作者信息

Brown Amy C, Onopa Janet, Holck Peter, Kaufusi Pakieli, Kabasawa Derek, Craig Winston J, Dragull Klaus, Levine Arieh M, Baker Jonathan D

机构信息

Department of Complementary & Alternative Medicine, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.

出版信息

Clin Toxicol (Phila). 2007 Jun-Aug;45(5):549-56. doi: 10.1080/15563650701365875.

DOI:10.1080/15563650701365875

PMID:17503265

Abstract

PURPOSE

To determine the effects of traditionally prepared kava beverages on the liver function tests of regular kava beverage consumers in a population of Tongan and non-Tongan residents of Hawaii (Oahu).

METHODS

The liver function tests of 31 healthy adult kava drinkers were compared against a control group of 31 healthy adult non-kava drinkers. Subjects were recruited from the general population, a kava bar, and Tongan kava drinking circles. The liver function profile included AST, ALT, ALP, GGT, and bilirubin (total and direct). Other tests included total protein, albumin, and screens for viral hepatitis and hemochromatosis when indicated.

RESULTS

Chronic kava beverage consumption was associated with elevation of GGT in 65% of the kava drinkers versus 26% in the controls (P = .005). ALP was elevated in 23% of kava drinkers versus 3% in the controls (P = .053).

CONCLUSION

Heavy kava beverage consumption was associated with significantly elevated GGT levels.

摘要

目的

确定传统制备的卡瓦饮料对夏威夷（瓦胡岛）汤加和非汤加居民中经常饮用卡瓦饮料者肝功能检查的影响。

方法

将31名健康成年卡瓦饮料饮用者的肝功能检查结果与31名健康成年非卡瓦饮料饮用者的对照组进行比较。受试者从普通人群、卡瓦酒吧和汤加卡瓦饮用圈子中招募。肝功能指标包括谷草转氨酶（AST）、谷丙转氨酶（ALT）、碱性磷酸酶（ALP）、γ-谷氨酰转肽酶（GGT）和胆红素（总胆红素和直接胆红素）。其他检查包括总蛋白、白蛋白，以及在有指征时筛查病毒性肝炎和血色素沉着症。