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2009 年 H1N1 流感大流行:21 世纪首次大流行期间美国的现场和流行病学调查。

2009 H1N1 influenza pandemic: field and epidemiologic investigations in the United States at the start of the first pandemic of the 21st century.

机构信息

National Center for Immunization and Respiratory Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

Clin Infect Dis. 2011 Jan 1;52 Suppl 1:S1-3. doi: 10.1093/cid/ciq005.

DOI:10.1093/cid/ciq005
PMID:21342879
Abstract

In April, 2009, CDC identified a novel influenza A virus detected from 2 children with febrile respiratory illness in southern California. The virus quickly emerged and spread globally and by 5 May, confirmed cases had been reported from 41 US states and 21 countries worldwide. Since the virus had never been identified before, little was known about the characteristics of the virus and how the pandemic would progress-would it be severe, how efficient would viral transmission be, would transmission be sustainable, what would the spectrum of illness, factors associated with severe disease, and causes of death be, and what risk groups would be most affected? Field investigations and epidemiologic studies in the United States and elsewhere were critical in helping answer these questions and characterizing the virus and the pandemic. This supplement will report results from field and epidemiologic investigations conducted in the United States since April 2009.

摘要

2009 年 4 月,疾病预防控制中心从加利福尼亚州南部两名患有发热性呼吸道疾病的儿童身上发现了一种新型甲型流感病毒。该病毒迅速传播并在全球范围内蔓延,截至 5 月 5 日,美国 41 个州和全球 21 个国家均报告了确诊病例。由于这种病毒以前从未被发现过,因此人们对该病毒的特性以及大流行将如何发展知之甚少——它会很严重吗?病毒传播效率会有多高?传播是否可持续?疾病谱、与严重疾病相关的因素以及死亡原因是什么?哪些风险群体受影响最大?美国和其他国家的实地调查和流行病学研究对帮助回答这些问题以及对病毒和大流行进行特征描述至关重要。本增刊将报告自 2009 年 4 月以来在美国开展的实地和流行病学调查结果。

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