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[补骨脂中的两种新化合物]

[Two new compounds from Psoralea corylifolia L].

作者信息

Yang Tong-Tong, Li Jing, Qin Min-Jian, Zhao Ming, Ouyang Zhen, Fu Hai-Zhen

机构信息

School of Pharmacy, Jiangsu University, Zhenjiang 212013, China.

出版信息

Yao Xue Xue Bao. 2009 Dec;44(12):1387-90.

Abstract

To study the chemical constituents of the fruits of Psoralea corylifolia L., the constituents were isolated and purified by chromatography. Two new compounds were isolated from the ethyl acetate-soluble fraction of the ethanol extract. On the basis of chemical and spectroscopic data 1D and 2D NMR, they were identified as 2-(3, 4-dihydroxyphenyl)-8, 8-dimethyl-8H-pyrano[2, 3-h]chromen-4-one (1) and 5-(2-hydroxyl-1-methyl)-ethyl-4, 5-dihydrofurano[2, 3-h](4'-hydroxyl-3', 5'-dimethoxy)-isoflavone (2), and named as coryfolia D and bavarigenin separately.

摘要

为研究补骨脂果实的化学成分,采用色谱法对其成分进行分离纯化。从乙醇提取物的乙酸乙酯可溶部分分离得到两个新化合物。根据化学和光谱数据(一维和二维核磁共振),它们分别被鉴定为2-(3,4-二羟基苯基)-8,8-二甲基-8H-吡喃并[2,3-h]色原酮-4-酮(1)和5-(2-羟基-1-甲基)乙基-4,5-二氢呋喃并2,3-h异黄酮(2),并分别命名为补骨脂素D和巴瓦吉宁。

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