Department of Surgery, University of California San Diego, 200 Arbor Drive, #8400, San Diego, CA 92103, USA.
Surg Endosc. 2011 Jul;25(7):2254-60. doi: 10.1007/s00464-010-1543-7. Epub 2011 Feb 27.
In recent years, more and more large, population-level databases have become available for clinical research. The size and complexity of these databases often present a methodological challenge for investigators. We propose that a "protocol" may facilitate the research process using these databases. In addition, much like the structured History and Physical (H&P) helps the audience appreciate the details of a patient case more systematically, a formal outcomes research protocol can also help in the systematic evaluation of an outcomes research manuscript.
近年来，越来越多的大型人群数据库可用于临床研究。这些数据库的规模和复杂性常常给研究人员带来方法学上的挑战。我们提出，“方案”可能会促进使用这些数据库进行研究的过程。此外，就像结构化的病史和体检 (H&P) 有助于听众更系统地了解患者病例的细节一样，正式的结局研究方案也有助于系统地评估结局研究手稿。
