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2003-2009 年日本诺如病毒感染的季节性模式和基因型分布。

Seasonal pattern and genotype distribution of sapovirus infection in Japan, 2003-2009.

机构信息

Department of Developmental Medical Sciences, Institute of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

出版信息

Epidemiol Infect. 2012 Jan;140(1):74-7. doi: 10.1017/S0950268811000240. Epub 2011 Mar 4.

DOI:10.1017/S0950268811000240
PMID:21371364
Abstract

Sapovirus, a member of the family Caliciviridae, is one of the major causative agents of viral gastroenteritis affecting all age groups. A total of 3232 faecal specimens collected from infants and children with gastroenteritis in five different regions of Japan during 2003-2009 were examined for sapovirus by reverse transcription-polymerase chain reaction. Sapoviruses were detected in 131 (4·05%) patients with the peak observed mainly in the cold season (November-March) in Japan during 2003-2009. During the last 6 years, sapovirus GI/1 was the predominant strain in Japan followed by GIV, GII/3, GII/6, GII/2, GII/12 and GI, respectively.

摘要

肠道病毒,小核糖核酸病毒科的一个成员,是影响所有年龄段人群的病毒性肠胃炎的主要病原体之一。2003-2009 年期间,在日本五个不同地区收集了 3232 份患有肠胃炎的婴幼儿粪便标本,通过反转录-聚合酶链反应对肠道病毒进行了检测。在 131 例(4.05%)患者中检测到肠道病毒,主要发生在日本的寒冷季节(11 月至 3 月)。在过去的 6 年中,肠道病毒 GI/1 是日本的主要流行株,其次是 GIV、GII/3、GII/6、GII/2、GII/12 和 GI。

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