National Fisheries Research and Development Institute, Ministry of Food, Agriculture, Forestry and Fisheries, 152-1 Haean-ro, Gijang-eup, Gijang-gun, Busan, Republic of Korea.
J Food Prot. 2011 Mar;74(3):380-6. doi: 10.4315/0362-028X.JFP-10-307.
The antimicrobial resistance patterns to 15 antimicrobial agents of Vibrio parahaemolyticus and Vibrio alginolyticus isolated from farmed fishes, including olive flounder (Paralichthys olivaceus), black rockfish (Sebastes schlegeli), red sea bream (Pagrus major), and sea bass (Lateolabrax japonicus), were investigated from 2005 through 2007. A total of 218 V. parahaemolyticus isolates and 153 V. alginolyticus isolates were obtained from the 180 fish samples collected from fish farms located along the southern coast of Korea. We found that 65.1% of V. parahaemolyticus and 85.6% of V. alginolyticus isolates showed antimicrobial resistance against more than one antimicrobial agent. The prevalence of resistance in V. parahaemolyticus isolates to ampicillin was highest (57.8%), followed by resistance to rifampin (11.9%), streptomycin (8.7%), and trimethoprim (6.4%). V. alginolyticus isolates were also most resistant to ampicillin (75.2%), followed by tetracycline (15.0%), trimethoprim (12.4%), and rifampin (9.8%). The prevalence of multiresistance to four or more antimicrobials was higher in V. alginolyticus (11.1%) than in V. parahaemolyticus (5%). Antimicrobial resistance rates per isolate of V. parahaemolyticus and V. alginolyticus possessing virulence genes were not different from those of the rest of the isolates.
2005 年至 2007 年，从养殖鱼类（包括牙鲆、青石斑鱼、大菱鲆和鲈鱼）中分离出的副溶血性弧菌和溶藻弧菌对 15 种抗菌药物的耐药模式进行了研究。从韩国南部沿海地区的 180 个养殖场采集的 180 个鱼样中获得了 218 株副溶血性弧菌和 153 株溶藻弧菌。我们发现，65.1%的副溶血性弧菌和 85.6%的溶藻弧菌对一种以上抗菌药物表现出耐药性。副溶血性弧菌对氨苄西林的耐药率最高（57.8%），其次是利福平（11.9%）、链霉素（8.7%）和甲氧苄啶（6.4%）。溶藻弧菌对氨苄西林的耐药率也最高（75.2%），其次是四环素（15.0%）、甲氧苄啶（12.4%）和利福平（9.8%）。4 种或 4 种以上抗菌药物耐药的多重耐药性在溶藻弧菌（11.1%）中比副溶血性弧菌（5%）更为普遍。携带毒力基因的副溶血性弧菌和溶藻弧菌的单个分离株的抗菌药物耐药率与其他分离株没有差异。
