Department of Bioengineering, Rice University, Houston, TX, USA.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 May-Jun;3(3):307-17. doi: 10.1002/wnan.138. Epub 2011 Mar 7.
Thermally responsive polymer-metal nanoparticle composites couple the ability of certain metal nanoparticles to convert external stimuli to heat with polymers that display sharp property changes in response to temperature changes, allowing for external control over polymer properties. These systems have been investigated for a variety of biomedical applications, including drug delivery, microfluidic valve control, and cancer therapy. This article focuses on three different size scales of this system: bulk systems (>1mm), nano- or microscale systems, and individual particle coatings. These composite systems will continue to be widely researched in the future for their vast potential in various biomedical applications.
温敏聚合物-金属纳米粒子复合材料结合了某些金属纳米粒子将外部刺激转化为热能的能力，以及对温度变化表现出急剧性能变化的聚合物，从而可以对外界控制聚合物的性能。这些系统已被广泛应用于各种生物医学领域，包括药物输送、微流控阀控制和癌症治疗等。本文主要关注该系统的三个不同的尺寸范围：大块系统（>1mm）、纳米或微尺度系统以及单个粒子涂层。由于其在各种生物医学应用中的巨大潜力，这些复合材料系统在未来将继续得到广泛研究。
