Song Youngsik, Azmand Hojjat Rostami, Seo Sang-Woo
Department of Electrical Engineering, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.
Sens Actuators A Phys. 2020 Jan 1;301. doi: 10.1016/j.sna.2019.111729. Epub 2019 Nov 9.
This paper presents rapid photothermal actuation of light-addressable, arrayed hydrogel columns in a macroporous silicon membrane. Au nanorods are incorporated into thermo-responsive p-NIPAAm hydrogel to utilize surface plasmon-induced local heating by near-infrared light. By measuring optical transmission through the fabricated membrane structure with Au nanorod embedded hydrogel, we have demonstrated that photothermal actuation of hydrogel can be done in two-dimensional, pixel-like configuration with high spatial and temporal resolutions. Benefiting from the hydrogel volume confinement within micron-sized pores, we have achieved sub-second response time of hydrogel photothermal actuation and its repeatable photothermal actuation on highly localized illuminated area. Considering that each hydrogel column is confined within each pore and different wavelength of light can be used to induce photothermal actuation of hydrogel's deswelling characteristics by modifying physical dimensions of Au nanorods, it has a potential for optically-addressable, multiplexed drug release systems with rapid response time.
本文展示了在大孔硅膜中对光寻址的阵列水凝胶柱进行快速光热驱动。将金纳米棒掺入热响应性聚N-异丙基丙烯酰胺（p-NIPAAm）水凝胶中，以利用近红外光的表面等离子体诱导局部加热。通过测量透过嵌入金纳米棒的水凝胶的预制膜结构的光传输，我们证明了水凝胶的光热驱动可以在二维像素状配置中以高空间和时间分辨率实现。受益于微米级孔隙内水凝胶体积的限制，我们实现了水凝胶光热驱动的亚秒级响应时间及其在高度局部照明区域上的可重复光热驱动。考虑到每个水凝胶柱都被限制在每个孔隙内，并且通过改变金纳米棒的物理尺寸，可以使用不同波长的光来诱导水凝胶去溶胀特性的光热驱动，它具有用于具有快速响应时间的光寻址多路复用药物释放系统的潜力。
