Pochi P E
Department of Dermatology, Boston University School of Medicine, Massachusetts 02118.
Annu Rev Med. 1990;41:187-98. doi: 10.1146/annurev.me.41.020190.001155.
Acne is a follicular disorder of the skin occurring in specialized pilosebaceous units on the face and trunk. An abnormality of the keratinizing epithelium of these follicles, thought to be due to the action of sebum synthesized and secreted by the androgen-sensitive sebaceous glands, leads to inflammation induced by the follicular bacterium, Propionibacterium acnes. Therapy involves treatments that modify these pathogenic factors and includes drugs with antikeratinizing, antibacterial, and antiseborrheic actions.
痤疮是一种发生在面部和躯干上特殊毛囊皮脂腺单位的毛囊性皮肤疾病。这些毛囊的角质形成上皮异常，被认为是由雄激素敏感皮脂腺合成和分泌的皮脂作用所致，会导致毛囊细菌痤疮丙酸杆菌引发炎症。治疗方法包括改变这些致病因素的治疗手段，且包括具有抗角质化、抗菌和抗皮脂溢作用的药物。
