Centers for Disease Control and Prevention, National Center for Injury Prevention and Control (NCIPC), 4770 Buford Hwy, NE, MS F-63, Atlanta, GA 30341-3717, USA Epidemic Intelligence Service, Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop E-92, Atlanta, GA 30333, USA Kansas Department of Health and Environment, Bureau of Health Promotion, 1000 SW Jackson St # 230, Topeka, KS 66612-1274, USA.
Pain. 2011 Jun;152(6):1249-1255. doi: 10.1016/j.pain.2010.12.036. Epub 2011 Mar 11.
Chronic pain is a common reason for medical visits, but prevalence estimates vary between studies and have rarely included drug treatment data. This study aimed to examine characteristics of chronic pain and its relation to demographic and health factors, and factors associated with treatment of pain with opioid analgesics. A chronic pain module was added to the 2007 Kansas Behavioral Risk Factor Surveillance System (response rate = 61%). Data on prevalence, duration, frequency, and severity of chronic pain, demographics, and health were collected from a representative sample of 4090 adults 18 years and older by telephone. Logistic regression was used to examine the association of both chronic pain and opioid use with demographic and health factors. Chronic pain was reported by 26.0% of the participants and was associated with activity limitations (adjusted odds ratio [AOR] = 3.6, 95% confidence interval [95% CI] 2.8-4.5), arthritis (AOR = 3.3, 95% CI 2.6-4.0), poor mental health (AOR = 2.0, 95% CI 1.4-2.8), poor overall health (AOR = 1.9; 95% CI 1.5-2.5), and obesity (AOR = 1.6; 95% CI 1.2-2.0). Of the 33.4% of people with pain who use prescription pain medication, 45.7% took opioids, including 36.7% of those with mild pain. Chronic pain affects a quarter of adults in Kansas and is associated with poor health. Opioid analgesics are the mainstay of prescribed pharmacotherapy in this group, even among those reporting mild pain. Chronic pain affects 26.0% of adults in the state of Kansas, U.S.A. Overall, 45.7% of people who take prescription drugs for chronic pain reported taking opioid analgesics.
慢性疼痛是就医的常见原因，但各研究中的流行率估计值存在差异，且很少纳入药物治疗数据。本研究旨在探讨慢性疼痛的特征及其与人口统计学和健康因素的关系，以及与使用阿片类镇痛药治疗疼痛相关的因素。在堪萨斯州行为风险因素监测系统 2007 年的基础上增加了慢性疼痛模块（应答率=61%）。通过电话对 4090 名 18 岁及以上的成年人进行了慢性疼痛的流行率、持续时间、频率和严重程度、人口统计学和健康数据的收集。采用 logistic 回归分析了慢性疼痛和阿片类药物使用与人口统计学和健康因素的相关性。26.0%的参与者报告患有慢性疼痛，并与活动受限（调整后比值比[OR] = 3.6，95%置信区间[95%CI] 2.8-4.5）、关节炎（OR = 3.3，95%CI 2.6-4.0）、心理健康状况差（OR = 2.0，95%CI 1.4-2.8）、整体健康状况差（OR = 1.9；95%CI 1.5-2.5）和肥胖（OR = 1.6；95%CI 1.2-2.0）相关。在有疼痛症状并使用处方止痛药的 33.4%的人群中，45.7%的人服用阿片类药物，其中轻度疼痛患者占 36.7%。慢性疼痛影响美国堪萨斯州四分之一的成年人，与健康状况不佳有关。阿片类镇痛药是该人群中处方药物治疗的主要药物，甚至在报告轻度疼痛的人群中也是如此。慢性疼痛影响美国堪萨斯州 26.0%的成年人。总体而言，45.7%服用处方药物治疗慢性疼痛的人报告服用阿片类镇痛药。
