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针对轻度认知障碍(MCI)老年人认知功能的非药物干预。

Non-pharmacological interventions on cognitive functions in older people with mild cognitive impairment (MCI).

机构信息

Institute of Biosciences, UNESP, Univ. Estadual Paulista, Department of Physical Education, Physical Activity and Aging Lab (LAFE), 1515, 24A ave. - Bela Vista, Rio Claro/SP, Zip Code: 13506-900, Brazil.

出版信息

Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):175-80. doi: 10.1016/j.archger.2011.02.014. Epub 2011 Mar 12.

Abstract

Mild cognitive impairment (MCI) can be a stage of pre-dementia. There is no consensus about pharmacological treatment for this population, so it is important to structure non-pharmacological interventions for increasing their cognitive reserve. We intended to analyze the effects of non-pharmacological interventions in the cognitive functions in older people with MC, in form of a systemic review. Data sources were the Web of Science, Biological Abstracts, Medline, Pub Med, EBSCHost, Scirus and Google Scholar. All studies were longitudinal trials, with MCI sample, aged>60 years, community-dwelling, and having cognitive functions as dependent variable. Seven studies, from 91 previously selected ones, were identified according to the inclusion criteria. Six studies used cognitive intervention, improving memory and one study used physical activity as intervention, improving executive functions. The results show evidence that physical activity and cognitive exercise may improve memory and executive functions in older people with MCI. But yet, more controlled studies are needed to establish a protocol of recommendations regarding the systemization of exercise, necessary to produce benefits in the cognitive functioning in older people with MCI.

摘要

轻度认知障碍 (MCI) 可能是痴呆前的一个阶段。对于这一人群,药物治疗尚无共识,因此,构建非药物干预措施以增加认知储备非常重要。我们旨在通过系统评价分析针对 MCI 老年人认知功能的非药物干预措施的效果。数据来源为 Web of Science、Biological Abstracts、Medline、Pub Med、EBSCHost、Scirus 和 Google Scholar。所有研究均为纵向试验,MCI 样本为年龄>60 岁、居住在社区、认知功能为因变量的人群。根据纳入标准,从最初选择的 91 项研究中确定了 7 项研究。6 项研究使用认知干预措施改善记忆力,1 项研究使用体力活动作为干预措施,改善执行功能。结果表明,体力活动和认知锻炼可能改善 MCI 老年人的记忆力和执行功能。但是,仍需要更多的对照研究来制定有关锻炼系统化的建议方案,这对于产生 MCI 老年人认知功能的益处是必要的。

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