Regional Laboratory of Public Health, East Macedonia-Thrace, Komotini, Greece.
Int J Gen Med. 2011 Jan 6;4:15-9. doi: 10.2147/IJGM.S15654.
There are at least 40 types of Legionella bacteria, half of which are capable of producing disease in humans. The Legionella pneumophila bacterium, the root cause of Legionnaires' disease, causes 90% of legionellosis cases.
We describe the case of a 60-year-old woman with a history of diabetes mellitus and arterial hypertension who was admitted to our hospital with fever and symptoms of respiratory infection, diarrhea, and acute renal failure. We used real-time polymerase chain reaction (PCR) to detect L. pneumophila DNA in peripheral blood and serum samples and urine antigen from a patient with pneumonia. Legionella DNA was detected in all two sample species when first collected.
Since Legionella is a cause of 2% to 15% of all community-acquired pneumonias that require hospitalization, legionellosis should be taken into account in an atypical pulmonary infection and not be forgotten. Moreover, real-time PCR should be considered a useful diagnostic method.
至少有 40 种军团菌，其中一半能够使人类患病。军团菌肺炎杆菌是导致军团病的根源，引起 90%的军团病病例。
我们描述了一位 60 岁女性的病例，她有糖尿病和动脉高血压病史，因发热和呼吸道感染、腹泻和急性肾衰竭而住进我院。我们使用实时聚合酶链反应（PCR）检测了外周血和血清样本以及肺炎患者尿抗原中的嗜肺军团菌 DNA。首次采集时，在两种样本中均检测到了军团菌 DNA。
由于军团菌是导致 2%至 15%需要住院治疗的社区获得性肺炎的原因之一，因此在非典型肺部感染中应考虑军团菌病，不要忽视它。此外，实时 PCR 应被视为一种有用的诊断方法。
