Wendling D, Dalphin J C, Toson B, Depierre A, Guidet M
Service de Rhumatologie, Centre Hospitalier Universitaire, Besancon, France.
Ann Rheum Dis. 1990 May;49(5):325-6. doi: 10.1136/ard.49.5.325.
Bronchoalveolar lavage and bronchial biopsies were performed in 15 patients with ankylosing spondylitis (AS) and 17 control subjects. There was no difference in total cell count, number of lymphocytes, CD4+/CD8+ ratio, or beta 2 microglobulin concentrations in bronchoalveolar lavage fluid between these two groups. Bronchoalveolar lavage IgA concentrations were not increased, but bronchial IgA deposits were more common in AS. This study failed to show any subclinical alveolitis in AS.
对15例强直性脊柱炎(AS)患者和17名对照者进行了支气管肺泡灌洗和支气管活检。两组之间支气管肺泡灌洗液中的总细胞计数、淋巴细胞数量、CD4+/CD8+比值或β2微球蛋白浓度没有差异。支气管肺泡灌洗IgA浓度没有升高,但AS患者支气管IgA沉积更常见。这项研究未能显示AS存在任何亚临床肺泡炎。