Institute of Organic Chemistry with the Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Nat Prod Res. 2011 Mar;25(6):606-13. doi: 10.1080/14786419.2010.488235.
From a biologically active extract of Indonesian propolis from East Java, 11 compounds were isolated and identified: four alk(en)ylresorcinols (obtained as an inseparable mixture) (1-4) were isolated for the first time from propolis, along with four prenylflavanones (6-9) and three cycloartane-type triterpenes (5, 10 and 11). The structures of the components were elucidated based on their spectral properties. All prenylflavanones demonstrated significant radical scavenging activity against diphenylpicrylhydrazyl radicals, and compound 6 showed significant antibacterial activity against Staphylococcus aureus. For the first time Macaranga tanarius L. and Mangifera indica L. are shown as plant sources of Indonesian propolis.
从印度尼西亚东爪哇的生物活性蜂胶提取物中分离并鉴定了 11 种化合物：4 种烯丙基苯并二酚（作为不可分割的混合物获得）（1-4）是首次从蜂胶中分离出来的，此外还有 4 种prenylflavanones（6-9）和 3 种环阿尔烷型三萜（5、10 和 11）。根据光谱性质阐明了组分的结构。所有prenylflavanones均表现出对二苯基苦味肼自由基的显著清除活性，并且化合物 6 对金黄色葡萄球菌表现出显著的抗菌活性。首次证明 Macaranga tanarius L.和 Mangifera indica L.是印度尼西亚蜂胶的植物来源。
