[乳腺癌癌症治疗功能评估问卷（FACT-B+4）。西班牙语版本验证]

[Functional Assessment of Cancer Therapy Questionnaire for Breast Cancer (FACT-B+4). Spanish version validation].

作者信息

Belmonte Martínez Roser, Garin Boronat Olatz, Segura Badía Marcel, Sanz Latiesas Javier, Marco Navarro Ester, Ferrer Fores Montserrat

机构信息

Servei de Medicina Física i Rehabilitació, Hospital Mar-Esperança, Parc de Salut Mar, Barcelona, Spain.

出版信息

Med Clin (Barc). 2011 Dec 10;137(15):685-8. doi: 10.1016/j.medcli.2010.11.028. Epub 2011 Mar 21.

DOI:10.1016/j.medcli.2010.11.028

PMID:21420133

Abstract

BACKGROUND AND OBJECTIVES

To evaluate the acceptability, reliability, validity, and sensitivity to change of the Spanish version of the FACT-B+4 questionnaire, designed to assess the health related quality of life (HRQL) in breast cancer.

PATIENTS AND METHODS

Prospective study with 2 samples: patients with incident breast cancer (n=104) evaluated before and after surgery; and patients with chronic lymphedema of the upper extremity (n=30), evaluated twice in 7days. HRQL was assessed using the generic instrument SF-36 and the specific one FACT-B+4.

RESULTS

Reliability coefficients were ≥ 0.7 for most scores. The Physical wellbeing, Breast Cancer, Arm and TOI scores discriminated between patients with and without chemotherapy (p<0.05), while the Arm scale discriminated between patients with and without axillary surgery (p<0.001). In the worsening sub-sample, the FACT-B+4 detected changes in Physical, Emotional and Functional Wellbeing, and TOI scores.

CONCLUSIONS

The metric characteristics of the Spanish version of the FACT-B+4 are similar to the original questionnaire and support its equivalence, documenting its suitability for use in our country or in international studies.

摘要

背景与目的

评估用于评估乳腺癌患者健康相关生活质量（HRQL）的西班牙文版FACT - B + 4问卷的可接受性、可靠性、有效性及对变化的敏感性。

患者与方法

采用前瞻性研究，分两个样本：新发乳腺癌患者（n = 104）在手术前后进行评估；上肢慢性淋巴水肿患者（n = 30）在7天内进行两次评估。使用通用工具SF - 36和特定工具FACT - B + 4评估HRQL。

结果

大多数评分的可靠性系数≥0.7。身体幸福感、乳腺癌、手臂和TOI评分在接受化疗和未接受化疗的患者之间存在差异（p < 0.05），而手臂量表在接受腋窝手术和未接受腋窝手术的患者之间存在差异（p < 0.001）。在病情恶化的子样本中，FACT - B + 4检测到身体、情感和功能幸福感以及TOI评分的变化。