Wanchai Ausanee, Armer Jane M, Stewart Bob R
Boromarajonani College of Nursing, Buddhachinaraj, Phitsanulok, Thailand.
Clin J Oncol Nurs. 2011 Apr;15(2):203-14. doi: 10.1188/11.CJON.203-214.
Cancer-related fatigue (CRF) is a distressing symptom that affects the quality of life (QOL) of patients with breast cancer and their families. The effectiveness of pharmacologic therapies alone has not been sufficient in the management of CRF; therefore, a combination of pharmacologic and nonpharmacologic approaches is justified. The purpose of this article is to critically review the literature related to nonpharmacologic supportive strategies in enhancing QOL among patients with breast cancer experiencing CRF. The results show that exercises (e.g., home-based exercise, supervised exercise), education and counseling, sleep therapy, and complementary therapy are feasible as effective nonpharmacologic supportive interventions to improve QOL in patients with breast cancer suffering from CRF. Therefore, nurses may consider these nonpharmacologic supportive strategies as adjunctive interventions to pharmacologic interventions in enhancing QOL for patients with breast cancer experiencing CRF. However, because previous studies had some methodologic limitations, such as small sample size, lack of objective measures, or predominantly Caucasian sample, future research to further explore nonpharmacologic interventions in this area is warranted.
癌症相关疲劳（CRF）是一种令人痛苦的症状，会影响乳腺癌患者及其家人的生活质量（QOL）。仅靠药物治疗在管理CRF方面并不充分；因此，药物和非药物方法相结合是合理的。本文的目的是批判性地回顾与非药物支持策略相关的文献，这些策略可提高患有CRF的乳腺癌患者的生活质量。结果表明，运动（如居家运动、有监督的运动）、教育与咨询、睡眠治疗以及补充疗法作为有效的非药物支持干预措施，对于改善患有CRF的乳腺癌患者的生活质量是可行的。因此，护士可将这些非药物支持策略视为药物干预的辅助干预措施，以提高患有CRF的乳腺癌患者的生活质量。然而，由于先前的研究存在一些方法学上的局限性，如样本量小、缺乏客观测量方法或样本主要为白种人，因此有必要开展进一步探索该领域非药物干预措施的未来研究。
