Department of Bioengineering, Stanford University, Stanford, California, USA.
Nat Methods. 2011 Apr;8(4):311-4. doi: 10.1038/nmeth0411-311.
Methods for genomic analysis at single-cell resolution enable new understanding of complex biological phenomena. Single-cell techniques, ranging from flow cytometry and microfluidics to PCR and sequencing, are used to understand the cellular composition of complex tissues, find new microbial species and perform genome-wide haplotyping.
单细胞分辨率的基因组分析方法为复杂生物现象提供了新的认识。单细胞技术,包括流式细胞术和微流控技术、PCR 和测序,用于了解复杂组织的细胞组成、发现新的微生物物种和进行全基因组单倍型分析。