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臭氧对牙釉质的微观结构形态变化的影响。

Ozone and microstructural morphological changes of tooth enamel.

机构信息

1st Department of Dentistry, Faculty of Dental Medicine, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania;

出版信息

Rom J Morphol Embryol. 2022 Jul-Sep;63(3):539-544. doi: 10.47162/RJME.63.3.08.

DOI:10.47162/RJME.63.3.08
PMID:36588492
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9926147/
Abstract

The paper aims to study the impact of ozone (O3) treatment on the microstructural changes of the tooth enamel after the treatment at different time intervals. The ozonation was performed with gaseous O3 produced by HealOzone X4, the demineralization level was measured with the DiagnoDent Pen 2190 device, and the microstructure changes of enamel surface were observed using scanning electron microscopy (SEM) analysis. The results showed the exposure to O3 for 40-50 seconds enhanced enamel micro-hardness and ensures a rate of remineralization between 96.82-97.38%. In conclusion, in search of new minimally invasive solutions in the treatment of caries and to offer antimicrobial support of the oral cavity, the use of O3 as an alternative therapy to classical solutions may be a viable solution in dentistry.

摘要

本文旨在研究不同时间间隔臭氧(O3)处理后对牙釉质微观结构变化的影响。臭氧处理使用 HealOzone X4 产生的气态 O3 进行,脱矿水平用 DiagnoDent Pen 2190 设备测量,使用扫描电子显微镜(SEM)分析观察牙釉质表面的微观结构变化。结果表明,暴露于 O3 40-50 秒可增强牙釉质的显微硬度,并确保再矿化率在 96.82-97.38%之间。总之,为了寻找治疗龋齿的微创新方法,并为口腔提供抗菌支持,臭氧作为传统解决方案的替代疗法,在牙科领域可能是一种可行的解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/a8b474e02a00/RJME-63-3-539-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/7e7d24143b8a/RJME-63-3-539-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/d8140835936e/RJME-63-3-539-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/262b639e4385/RJME-63-3-539-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/1e194498a9c9/RJME-63-3-539-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/a8b474e02a00/RJME-63-3-539-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/7e7d24143b8a/RJME-63-3-539-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/d8140835936e/RJME-63-3-539-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/262b639e4385/RJME-63-3-539-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/1e194498a9c9/RJME-63-3-539-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c9/9926147/a8b474e02a00/RJME-63-3-539-fig5.jpg

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本文引用的文献

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Ozone in Medicine. The Low-Dose Ozone Concept and Its Basic Biochemical Mechanisms of Action in Chronic Inflammatory Diseases.医学中的臭氧。低剂量臭氧概念及其在慢性炎症性疾病中的基本生化作用机制。
Int J Mol Sci. 2021 Jul 23;22(15):7890. doi: 10.3390/ijms22157890.
2
Ozone therapy a new vista in dentistry: integrated review.臭氧疗法在牙科中的新视野:综合评论。
Med Gas Res. 2020 Oct-Dec;10(4):189-192. doi: 10.4103/2045-9912.304226.
3
Effectiveness and Safety of Ozone Therapy in Dental Caries Treatment: Systematic Review and Meta-analysis.
医学与牙科中的臭氧疗法:文献综述
Dent J (Basel). 2023 Aug 7;11(8):187. doi: 10.3390/dj11080187.
臭氧疗法治疗龋齿的有效性和安全性:系统评价和荟萃分析。
J Evid Based Dent Pract. 2020 Dec;20(4):101472. doi: 10.1016/j.jebdp.2020.101472. Epub 2020 Jul 29.
4
Effect of nano-hydroxyapatite and ozone on approximal initial caries: a randomized clinical trial.纳米羟基磷灰石和臭氧对邻面早期龋的作用:一项随机临床试验。
Sci Rep. 2020 Jul 7;10(1):11192. doi: 10.1038/s41598-020-67885-8.
5
The hidden structure of human enamel.人类牙釉质的隐藏结构。
Nat Commun. 2019 Sep 26;10(1):4383. doi: 10.1038/s41467-019-12185-7.
6
Clinical utility of ozone therapy in dental and oral medicine.臭氧疗法在牙科和口腔医学中的临床应用
Med Gas Res. 2019 Jul-Sep;9(3):163-167. doi: 10.4103/2045-9912.266997.
7
Clinical antibacterial effectiveness Healozone Technology after incomplete caries removal.临床抗菌效果——不完全去腐后 Healozone 技术。
Eur J Paediatr Dent. 2019 Mar;20(1):73-78. doi: 10.23804/ejpd.2019.20.01.14.
8
DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE.牙釉质形成及其对口腔健康与疾病的影响
Physiol Rev. 2017 Jul 1;97(3):939-993. doi: 10.1152/physrev.00030.2016.
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Open Dent J. 2017 Jan 31;11:65-70. doi: 10.2174/1874210601711010065. eCollection 2017.
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