Goossens An
Department of Dermatology, Contact Allergy Unit, K. U. Leuven, 3000 Leuven, Belgium.
J Allergy (Cairo). 2011;2011:467071. doi: 10.1155/2011/467071. Epub 2011 Feb 21.
Contact-allergic reactions to cosmetics may be delayed-type reactions such as allergic and photo-allergic contact dermatitis, and more exceptionally also immediate-type reactions, that is, contact urticaria. Fragrances and preservative agents are the most important contact allergens, but reactions also occur to category-specific products such as hair dyes and other hair-care products, nail cosmetics, sunscreens, as well as to antioxidants, vehicles, emulsifiers, and, in fact, any possible cosmetic ingredient. Patch and prick testing to detect the respective culprits remains the golden standard for diagnosis, although additional tests might be useful as well. Once the specific allergens are identified, the patients should be informed of which products can be safely used in the future.
化妆品的接触性过敏反应可能是迟发型反应,如过敏性和光过敏性接触性皮炎,更罕见的也可能是速发型反应,即接触性荨麻疹。香料和防腐剂是最重要的接触性过敏原,但对特定类别的产品如染发剂和其他护发产品、指甲化妆品、防晒霜以及抗氧化剂、载体、乳化剂,实际上是任何可能的化妆品成分也会发生反应。尽管其他检测可能也有用,但通过斑贴试验和点刺试验来检测各自的罪魁祸首仍然是诊断的金标准。一旦确定了特定的过敏原,就应告知患者未来哪些产品可以安全使用。