Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, New York, USA.
Curr Opin Allergy Clin Immunol. 2011 Jun;11(3):236-42. doi: 10.1097/ACI.0b013e3283464cf0.
The purpose of this review is to provide a review of studies examining health-related quality of life (HRQL) in food-allergic individuals, with an emphasis on publications since 2007.
Over the past few years, an increasing number of studies have addressed the impact that food allergy has on HRQL. Many studies have used generic quality-of-life instruments to compare HRQL between food-allergic patients and healthy controls or between food-allergic patients and persons with other disease states. A significant achievement for this area of investigation is the existence of validated, disease-specific quality-of-life instruments for all age groups. These have been validated in multiple countries and translated into multiple languages.
Food allergy clearly affects a patient's HRQL. With validated, disease-specific instruments to measure HRQL, researchers will be able to use HRQL as an end-point in therapeutic clinical trials, and clinicians will have a further aid in caring for patients suffering from food allergies.
本文旨在对研究食物过敏个体健康相关生活质量（HRQL）的文献进行综述，重点关注 2007 年以来的出版物。
在过去的几年中，越来越多的研究关注食物过敏对 HRQL 的影响。许多研究使用通用生活质量工具来比较食物过敏患者与健康对照者或食物过敏患者与其他疾病患者之间的 HRQL。该研究领域的一个重要成就是为所有年龄段的患者都制定了经过验证的、特定于疾病的生活质量工具。这些工具已在多个国家得到验证，并翻译成多种语言。
食物过敏显然会影响患者的 HRQL。有了经过验证的、特定于疾病的 HRQL 测量工具，研究人员将能够将 HRQL 用作治疗性临床试验的终点，临床医生也将在照顾食物过敏患者方面得到进一步的帮助。
