新型电学法用于早期检测血培养中的活细菌。
Novel electrical method for early detection of viable bacteria in blood cultures.
机构信息
Department of Biological Engineering, University of Missouri, Columbia, Missouri 65211-5200, USA.
出版信息
J Clin Microbiol. 2011 Jun;49(6):2286-9. doi: 10.1128/JCM.00369-11. Epub 2011 Apr 6.
Abstract
We present a novel electrical method for detecting viable bacteria in blood cultures that is 4 to 10 times faster than continuous monitoring blood culture systems (CMBCS) like the Bactec system. Proliferating bacteria are detected via an increase in the bulk capacitance of suspensions, and the threshold concentration for detection is ∼ 10(4) CFU/ml (compared to ∼ 10(8) CFU/ml for the Bactec system).
摘要
我们提出了一种新颖的电学法，用于检测血液培养物中的活菌，其速度比 Bactec 系统等连续监测血培养系统 (CMBCS)快 4 至 10 倍。通过悬浮液的体电容增加来检测增殖细菌，检测的阈值浓度约为 10(4) CFU/ml（与 Bactec 系统的约 10(8) CFU/ml 相比）。
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