经等离子体氮化处理的钛表面的成骨细胞样细胞黏附。
Osteoblastlike cell adhesion on titanium surfaces modified by plasma nitriding.
机构信息
Departamento de Odontologia, Universidade Federal do Rio Grande do Norte, Natal/RN, Brazil.
出版信息
Int J Oral Maxillofac Implants. 2011 Mar-Apr;26(2):237-44.
PURPOSE
The aim of this study was to evaluate the characteristics of various titanium surfaces modified by cold plasma nitriding in terms of adhesion and proliferation of rat osteoblastlike cells.
MATERIALS AND METHODS
Samples of grade 2 titanium were subjected to three different surface modification processes: polishing, nitriding by plasma direct current, and nitriding by cathodic cage discharge. To evaluate the effect of the surface treatment on the cellular response, the adhesion and proliferation of osteoblastlike cells (MC3T3) were quantified and the results were analyzed by Kruskal-Wallis and Friedman statistical tests. Cellular morphology was observed by scanning electron microscopy.
RESULTS
There was more MC3T3 cell attachment on the rougher surfaces produced by cathodic cage discharge compared with polished samples (P < .05).
CONCLUSIONS
Plasma nitriding improves titanium surface roughness and wettability, leading to osteoblastlike cell adhesion.
目的
本研究旨在评估经冷等离体离子氮化处理的各种钛表面在大鼠成骨样细胞黏附与增殖方面的特性。
材料与方法
对 2 级钛样本进行了三种不同的表面改性处理：抛光、直流等离子体氮化和阴极笼放电氮化。为了评估表面处理对细胞反应的影响，通过 Kruskal-Wallis 和 Friedman 统计检验对成骨样细胞（MC3T3）的黏附和增殖进行了量化分析。通过扫描电子显微镜观察细胞形态。
结果
与抛光样本相比，阴极笼放电处理产生的更粗糙表面上有更多的 MC3T3 细胞黏附（P＜.05）。
结论
等离子体氮化可提高钛表面粗糙度和润湿性，从而促进成骨样细胞黏附。
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