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抗体结合增强了多聚(dt)45 通过α-溶血素纳米孔的易位。

Enhanced translocation of poly(dt)45 through an α-hemolysin nanopore by binding with antibody.

机构信息

Shanghai Key Laboratory of Functional Materials Chemistry & Department of Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, PR China.

出版信息

Chem Commun (Camb). 2011 May 28;47(20):5690-2. doi: 10.1039/c0cc05787h. Epub 2011 Apr 14.

DOI:10.1039/c0cc05787h
PMID:21491051
Abstract

The translocation time of poly(dT)(45) through an α-hemolysin pore was reduced in the presence of a DNA-binding Fab fragment. The Fab acts as a rudder to steer the DNA into the pore.

摘要

多聚（dT）（45）穿过α-溶血素孔的转位时间在 DNA 结合 Fab 片段存在的情况下减少。Fab 片段充当舵手将 DNA 引导入孔中。

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