Anses Laboratoire de Niort, 60 rue de Pied de Fond, BP 3081, 79012 Niort Cedex, France.
Vet Parasitol. 2011 Aug 25;180(3-4):354-7. doi: 10.1016/j.vetpar.2011.03.022. Epub 2011 Mar 24.
Many compounds have been screened for their potential anti-cryptosporidial activity in ruminants but none of them has been totally efficient in controlling the disease. A product containing activated charcoal and wood vinegar liquid demonstrated a good efficacy in controlling clinical signs and oocyst excretion in calves experimentally infected. This product (Obionekk(®), Obione, Charentay, France) was given to goat kids in field conditions. The product was administered in a preventive way at the dose rate of 3.75 g/day/kid of Obionekk(®) from the age of 3 days to the age of 17 days in suspension in milk replacer twice or three times a day. A significant reduction of oocyst excretion was observed when the product was given 3 times a day when compared to control group. The clinical signs (diarrhoea) were significantly reduced whatever the rhythm of distribution when compared to control group. These results demonstrated the efficacy of Obionekk(®) in preventing cryptosporidiosis in goat kids in field conditions.
许多化合物已被筛选用于其在反刍动物中的潜在抗隐孢子虫活性，但没有一种化合物能完全有效地控制该疾病。一种含有活性炭和木醋液的产品在控制犊牛感染的临床症状和卵囊排泄方面显示出良好的疗效。该产品（Obionekk®，Obione，Charentay，法国）在田间条件下用于山羊幼崽。该产品以混悬液的形式在牛奶替代品中每天给药 3 次，每次剂量为 3.75 g/幼崽，从 3 天龄到 17 天龄，预防给药，每天 2 或 3 次。与对照组相比，当每天给药 3 次时，观察到卵囊排泄明显减少。与对照组相比，无论分配节律如何，临床症状（腹泻）均显著减少。这些结果表明 Obionekk®在预防田间条件下山羊幼崽隐孢子虫病方面的有效性。
